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Cabutazone injection | Phenylbutazone | non-steroidal anti-inflammatory drug | for horses, sheep, goat, cattle, camel and dogs

for veterinary use only

Cabutazone is one of the anti inflammatory drugs for dog, horse, cattle, sheep, goat and camel can be used for various disease conditions as: dog joint problems, equine arthritis, chronic laminitis and used as a drug for fever in horse and the other mentioned species in addition to its use as an animal pain killer in injuries and after surgeries.

composition:

Each 1 ml of Cabutazone contains Phenylbutazone 200 mg.

Properties:

-Phenylbutazone is a non-steroidal anti-inflammatory drug  related to the pyrazolone derivative.


-The anti-inflammatory and analgesic effects of phenylbutazone depend on its ability to inhibit hypothalamic cyclo-oxygenase
leading to reduced synthesis of prostaglandins and related compounds.


-This is followed by activation of heat loss mechanisms, i.e. panting, sweating and peripheral vasodilatation, and inhibition of thermogenesis.


-It also has the ability to trap or scavenge toxic oxygen-free radicals.

 

Indications:

-Cabutazone is indicated for the treatment of musculoskeletal and joint disorders such as arthritis, rheumatoid, myositis, acute and chronic laminitis, bursitis, tendinitis, and carpitis.

-also indicated for the reduction of post-surgical soft tissue reaction, pain and painful injuries in horses, cattle, camels, sheep, goats, and dogs.


-It is also indicated as an adjunct to a specific therapy in cases of pneumonia, mastitis, bacterial scours and endotoxic shock horses, cattle, camels, sheep, goats, and dogs.

Dose:

( By Slowly I/V or deep I/M in all animals except in equine by slowly I/V only).
4 mg / kg body weight.

Warnings:

The administration should be limited to a maximum of five successive days in animals and two successive days in dogs.

Contraindication:

Not to be used in case of known hypersensitivity, cardiac, renal diseases, edema and a possibility of gastrointestinal ulceration.
Withdrawal period:
Meat: 12 days.
Milk: 4 days.

storage:

Store at a temperature not exceeding 30°C and To be used immediately after opening.

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