FOR VETERINARY USE ONLY WITH A PRESCRIPTION
Colistin Avico is a veterinary antibiotic used to treat diarrhea in sheep, brucellosis in cows, diarrhea in calves, mastitis in cows, and brucellosis in sheep for more details from byttara .com COLISTIN ''AVICO'' POWDER is a veterinary antibiotic with a bactericidal effect against bacterial infections in poultry, calves & lambs
Composition
Each 1 gm COLISTIN ”AVICO” POWDER contains
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Colistin
(as Colistin sulfate) ---600 000 I.U.
Properties
COLISTIN ”AVICO” POWDER is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like:
E. coli, Haemophilus and Salmonella spp.
Polymyxins interact strongly with phospholipids and penetrate into and disrupt the structure of cell membranes.
They disorganise the outer membrane of Gram-Negative bacteria by binding lipopolysaccharide (LPS, Endotoxin) through direct interaction with the anionic lipid region, thereby neutralizing the endotoxin capacity of LPS.
Colistin sulfate is poorly absorbed after oral administration, and serum concentrations are generally undetectable.
In chickens, residues in serum were detectable for up to 6 hours after administration in the drinking water.
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