For Veterinary Use Only With a Prescription.
NEW COLIPRIM is a wide spectrum veterinary antibiotic used for treatment of calves, lambs and poultry diseases including:
- salmonellosis in poultry .
- infectious coryza disease in poultry .
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Composition
Each 1 ml NEW COLIPRIM contains:
Trimethoprim 40 mg.
Sulphadiazine Sodium 200 mg.
Properties
NEW COLIPRIM liquid is an oral solution composed of trimethoprim and Sulphadiazine.
The action of the combination was proved to be bactericidal whereas the component separately only bacteriostatic as trimethoprim potentiates the antibacterial activity of Sulphadiazine against a wide range of Gram-positive and gram-negative bacteria.
Sulphonamides act as an analogue for para-aminobenzoic acid, (PABA) which is itself a part of the vitamin, folic acid.
In organisms that synthesize their own folic acid, sulphonamides as sulphadiazine act by blocking the synthesis of folic acid.
Sulphonamides are active against bacteria but not against higher organisms as bacteria synthetic their own folic acid whereas higher animals or higher organisms obtained folic acid from the diet.
Indications
NEW COLIPRIM liquid is a distinctive drug against a wide range of gram-positive and gram-negative bacteria, besides its bactericidal effects, it has an enzyme inhibiting activity.
It is used in the treatment of various infectious diseases, e.g. pasteurellosis, colibacillosis and Salmonellosis in poultry and other animals and infectious coryza in poultry.
It’s a distinctive drug against a wide range of Gram-positive and Gram-negative bacteria such as E. coli, Salmonella, Klebsiella, Brucella, Corynebacterium pyogenes, Pasteurella, Staphylococcus, Streptococcus, Enterobacter and Haemophilus.
Dosage and administration
Poultry: 2-4 ml per 5 litres of drinking water for 5 days.
Calves and Lambs: 2 ml per 15 kg of live body weight per day orally for 5 days.
withdrawal period
Poultry 5 days.
Calves and Lambs 14 days.
Eggs Not to be used in laying birds.
Contraindications & Warnings
Not to be used for animals with functional rumen.
Storage
Store in a dark place at a temperature below 30ºC.
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