For veterinary use only with a prescription

BACTECLEAN doxycycline is one of the most effective oral antibiotics for the treatment of respiratory infection in poultry, calves & lambs let’s know more about the product with Byttara

Composition

Each 1 gm BACTECLEAN contains
Doxycycline HCL –200 mg

Properties

-BACTECLEAN contains Doxycycline which has a broad spectrum of action against a wide range of Gram-positive and Gram-negative pathogenic bacteria, including some which are resistant to penicillin

-Organisms that are sensitive to this tetracycline in the concentration usually achieved in the body during treatment include, Bacillus anthracis, Bordetella spp., staphylococci, streptococci, mycoplasma, certain rickettsia, chlamydia, Actinomyces spp. as well as large viruses are also sensitive to doxycycline

-In addition, a report of the antimicrobial activity of doxycycline showed that,

-it is more effective than other tetracyclines against most species such as staphylococci and enterococci

-Doxycyclines bind reversibly to bacterial 30 S ribosome and inhibit protein synthesis, perhaps by several mechanisms

Indications

-BACTECLEAN is a comprehensive preparation that controls a wide range of diseases affecting poultry and large animals

-contains the broad-spectrum antibiotic Doxycycline

-indicated for the treatment and prevention of bacterial infection caused by gram-positive and gram-negative mycoplasma and bacteria such as colibacillosi, salmonellosis, CRD, airsacculitis, infectious coryza, infectious sinusitis in poultry pneumonia and enteritis in calves and lambs

Dosage

Poultry
Gm 1 per 2 liters of drinking water for 5-7 days
or at the rate of 7 mg doxycycline per 1 kg BW

Calves and Lambs
mg 5-10 Doxycycline per 1 kg BW to be used daily in the drinking water for 5-7 days

withdrawal period

Poultry: 10 days
Calves and Lambs: 21 days

Toxicity & Side Effects

-contains Doxycycline which has a lower affinity for binding with calcium and it may cause less teeth discoloration than other tetracyclines

-High doses of tetracyclines administered orally to ruminants seriously disrupt microfloral activity in the ruminoreticulum

-Elimination of gut flora in the monogastric eventually producing stasis animals reduces the synthesis and availability of the B vitamins and vitamin K from the large intestine with prolonged therapy, vitamin supplementation is a useful precaution

Interactions

The absorption of tetracyclines from the gastrointestinal tract is decreased by milk and milk products (less for doxycycline and minocycline), anti acids, kaolin and iron preparations

Tetracyclines gradually lose activity when diluted in infusion fluid and exposed to ultraviolet light a vitamins of the B- complex group, especially riboflavin, hasten this loss of activity in infusion fluids