Draxxin is for veterinary use only with a veterinarian's prescription

Draxxin is the strongest veterinary antibiotic that is effective in treating pneumonia in cattle and the best antibiotic for sheep to treat hoof rot Let's get to know the product details

Active ingredient and other ingredients

Tulathromycin … 100 mg/ml
Monoglycerin … 5 mg/ml
Draxxin colorless to slightly yellow solution for injection

Indications for use

Draxxin is used in the treatment of

cattle:
-treatment of bovine respiratory diseases associated with hemolysis, sensitive to tulathromycin.
-The presence of the disease in the herd must be established before treatment with metaphylactic.
-Treatment of bovine infectious bovine keratoconjunctivitis (IBK) associated with tulathromycin-sensitive

sheep:
-Treatment of early stages of infectious dermatitis (foot rot) associated with malignant nodule requiring systemic treatment.

Contraindications

Do not use Draxxin in cases of:

-Hypersensitivity of target animals to macrolide antibiotics
-Do not use concurrently with other macrolides or lincosamides
– In lactating animals producing milk for human consumption. -Pregnant animals, which are intended to produce milk for human consumption, within two months of expected delivery.

Adverse reactions

-Subcutaneous administration of Draxxin to cattle commonly causes transient pain reactions and localized swelling upon injection that can last up to 30 days.

-No such reactions have been observed in pigs and sheep after intramuscular administration.

-Extremely severe pathologic injection site reactions are common for approximately 30 days after injection in cows and pigs.

-In sheep, transient signs of discomfort (head shaking, injection site rubbing, retraction) are very common after intramuscular injection, and these signs disappear within a few minutes.

– If you notice any serious effects or other effects not mentioned in this package leaflet, please inform your veterinary surgeon.

Target species

cattle and sheep

Dosage and administration

-Cows are given 2.5 mg tolthromycin/kg body weight (equivalent to 1 ml/40 kg body weight) in A single subcutaneous injection.
For the treatment of cows weighing more than 300 kg, the dose is divided so that it does not exceed 7.5 ml injected at one site
-Sheep: 2.5 mg tulathromycin/kg body weight (equivalent to 1 ml/40 kg body weight), single intramuscular injection in the neck.
Recommendations for Draxxin
-It is recommended to treat animals in the early stages of the disease and evaluate the response to treatment within 48 hours after injection.

-If clinical symptoms of respiratory disease persist or increase, or if a relapse occurs, treatment should be changed, using another antibiotic, and continued until clinical symptoms resolve.

-To ensure correct dosage, body weight should be determined as accurately as possible to avoid underdosing. For multi-bottle insertion, a suction needle or multi-dose syringe is recommended to avoid excessive occlusion of the stopper.

withdrawal period

Cows (meat and offal): 22 days
Sheep (meat and offal): 16 days
Draxxin is not authorized for use in lactating animals producing milk for human consumption.

Do not use in pregnant animals, which are intended to produce milk for human consumption, within two months of expected delivery.

Special Storage Precautions

Keep out of sight and reach of children.
The drug does not require any special storage conditions
Do not use after the expiration date stated on the label after first opening the container: 28 days.

Special warnings

Special warnings for sheep:

-Effectiveness of antimicrobial treatment Foot rot may be reduced by other factors such as wet environmental conditions, as well as inadequate remote management. So, the treatment of foot rot should be done in conjunction with other herd management tools, e.g., providing a dry environment

-Antibiotic treatment of benign foot rot is not appropriate.

Draxxin has shown limited efficacy in sheep with severe clinical signs or chronic foot rot and should, therefore, only be given early on.
Special precautions for use in animals:

-The use of the drug should be based on the susceptibility testing of bacteria isolated from the animal.
-Official, national, and regional antimicrobial policies should be taken into account when using the drug.
Special precautions to be taken by the person administering the veterinary medicinal preparation to animals:
-Tolathromycin is an eye irritant in case of accidental eye exposure; flush immediately with clean water.
-Tolathromycin may cause allergic reactions by contact with the skin. In case of accidental spillage on the skin, wash the skin immediately with soap and water.
– In case of accidental self-injection, seek medical advice immediately and show the package leaflet or label to the doctor.
Pregnancy and lactation: Laboratory studies in rats and rabbits have yielded no evidence of teratogenic or fetotoxic effects or maternal toxicity.

Use only as per benefit/risk assessment by the responsible veterinarian.
-Interaction with other medicinal products and other forms of interaction: Do not use antimicrobials at the same time with a similar mode of action as other macrolides or lincosamides.
-Overdose (symptoms, emergency procedures, antidote): In cattle at doses of three, five, or ten times the recommended dose, transient signs attributable to injection site discomfort were observed and included restlessness, head shaking, ground trampling, and a brief decrease in feed intake.

-Mild myocardial degeneration was observed in cattle receiving 5 to 6 times the recommended dose.

-In piglets weighing approximately 10 kg, when given three or five times the therapeutic dose, transient signs attributable to injection site discomfort were observed and included excessive vocalization and restlessness.

-Lameness was also noted when the hind leg was used as the injection site.

-The drug should not be mixed with other veterinary medicinal products.