-For unobserved or non-detected estrus in beef cows, lactating dairy cows, and replacement beef and dairy heifers

-For treatment of pyometra or chronic endometritis in beef cows, lactating dairy cows, and replacement beef and dairy heifers

-For treatment of: mummified fetus in beef cows, lactating dairy cows, and replacement beef and dairy heifers ,and luteal cysts in beef cows, lactating dairy cows, and replacement beef and dairy heifers

– abortion of beef cows, lactating dairy cows, and replacement beef and dairy heifers

–estrus synchronization in beef cows, lactating dairy cows, and replacement beef and dairy heifers

– use with Fertagyl gonadorelin to synchronize estrous cycles to allow for fixed-time artificial insemination FTAI in lactating dairy cows.

-causes functional and morphological regression of the corpus luteum luteolysis in cattle.

-normal, non-pregnant cycling animals, this effect on the life span of the corpus luteum usually results in estrus 2 to 5 days after treatment.

-animals with prolonged luteal function (pyometra, mummified fetus, and luteal cysts), the induced luteolysis usually results in resolution of the condition and return to cyclicity.

Pregnant animals may abort depending on the stage of gestation.