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ZUPREVO | Tildipirosin | For bovine respiratory disease

For veterinary use only

COMPOSITION

ZUPREVO contains:
Active substance:
Tildipirosin 180 mg/ml
Excipients:
Citric acid monohydrate
Propylene glycol
Water for injections

PHARMACEUTICAL FORM

clear yellowish solution for injection containing 180 mg/ml of tildipirosin.

TARGET SPECIES

Cattle.

INDICATIONS

For the treatment and prevention of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni sensitive to tildipirosin.
The presence of the disease in the herd should be confirmed before preventive treatment.

DOSAGE FOR EACH SPECIES

Administer 4 mg tildipirosin/kg body weight (equivalent to 1 ml/45 kg body weight) once only.

METHOD AND ROUTE OF ADMINISTRATION

Subcutaneous use.

ADVICE ON CORRECT ADMINISTRATION

used for treatment of cattle over 450 kg body weight, divide the dose so that no more than 10 ml are injected at one site.
The rubber stopper of the vial may be safely punctured up to 20 times.
Otherwise, the use of a multiple-dose syringe is recommended.
To ensure correct dosage and to avoid underdosing, body weight should be determined as accurately as possible.
It is recommended to treat animals in the early stages of the disease and to evaluate the response to treatment within 2 to 3 days after injection. If clinical signs of respiratory disease persist or increase, treatment should be changed using another antibiotic and continued until clinical signs have resolved.

CONTRAINDICATIONS

Do not use  in case of hypersensitivity to macrolide antibiotics, citric acid monohydrate or propylene glycol.

 

ADVERSE REACTIONS

Pain on injection and injection site swellings are very common in treated animals. 

WITHDRAWAL PERIODS

Cattle (Meat and offal): 47 days.
Do not use it in lactating cattle producing milk for human consumption.
Do not use in pregnant cows or heifers within 2 months of expected parturition when the milk produced is intended for human consumption.

SPECIAL STORAGE CONDITIONS

Keep out of the reach and sight of children.
Do not store above 30 °C. or after the expiry date which is stated on the vial.
Shelf-life after first opening the vial: 28 days.

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