For veterinary use only
COMPOSITION
ZUPREVO contains:
Active substance:
Tildipirosin 180 mg/ml
Excipients:
Citric acid monohydrate
Propylene glycol
Water for injections
PHARMACEUTICAL FORM
clear yellowish solution for injection containing 180 mg/ml of tildipirosin.
TARGET SPECIES
Cattle.
INDICATIONS
For the treatment and prevention of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni sensitive to tildipirosin.
The presence of the disease in the herd should be confirmed before preventive treatment.
DOSAGE FOR EACH SPECIES
Administer 4 mg tildipirosin/kg body weight (equivalent to 1 ml/45 kg body weight) once only.
METHOD AND ROUTE OF ADMINISTRATION
Subcutaneous use.
ADVICE ON CORRECT ADMINISTRATION
used for treatment of cattle over 450 kg body weight, divide the dose so that no more than 10 ml are injected at one site.
The rubber stopper of the vial may be safely punctured up to 20 times.
Otherwise, the use of a multiple-dose syringe is recommended.
To ensure correct dosage and to avoid underdosing, body weight should be determined as accurately as possible.
It is recommended to treat animals in the early stages of the disease and to evaluate the response to treatment within 2 to 3 days after injection. If clinical signs of respiratory disease persist or increase, treatment should be changed using another antibiotic and continued until clinical signs have resolved.
CONTRAINDICATIONS
Do not use in case of hypersensitivity to macrolide antibiotics, citric acid monohydrate or propylene glycol.
ADVERSE REACTIONS
Pain on injection and injection site swellings are very common in treated animals.
WITHDRAWAL PERIODS
Cattle (Meat and offal): 47 days.
Do not use it in lactating cattle producing milk for human consumption.
Do not use in pregnant cows or heifers within 2 months of expected parturition when the milk produced is intended for human consumption.
SPECIAL STORAGE CONDITIONS
Keep out of the reach and sight of children.
Do not store above 30 °C. or after the expiry date which is stated on the vial.
Shelf-life after first opening the vial: 28 days.
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